RESEARCH LINES

  1. MALARIA AND OTHER INFECTIOUS DISEASES CONNECTED TO HUMAN MOBILITY

Objectives: provide evidences for a correct approach to manage little know and controversial aspects of malaria. Moreover contribute to know epidemiological, clinical and diagnostic aspects, with effects on health public, of vector-borne diseases and other emerging infections connected to human mobility. The biomedical research, which will come up beside clinical research, will be oriented to study new aspects of physiopathology, to search new diagnostic and prognostic markers of diseases connected to human mobility, through modern technological approaches (for example, genomics and proteomcs).

Ongoing macro-projects:

L1P1 – Critical aspects of malaria management

L1P2 – Vector-borne (imported and autochthonous) infections

L1P3 – Progresses in the diagnosis and in the pathophysiology knowledge of vector-borne infections

L1P4 – Evaluation of drug efficacy for Covid-19

L1P5 – Clinical and epidemiological characteristics of Covid-19

L1P6 – Improving the diagnosis and the pathophysiology knowledge of SARS-CoV-2

L1P7 – Infections in a global health perspective

  1. STRONGYLOIDOSIS

Objectives: contribute to bring out the “burden of disease” represented by the strongyloidosis and to foster a national (screening and patient at risk of immunosuppression) and international (addition of strongyloidosis in WHO programmes of parasitosis in endemic countries control) integrated strategy of control. The biomedical research, collaborating with the clinical research, will be oriented to the study of new physiopathology aspects, new diagnostic and prognostic markers of strongyloidosis, through the most modern technologies of genomics and proteomics.

Ongoing macro-projects:

L2P1 – Strong treat – Randomized Clinical Trial on Multiple versus Single Dose Ivermectin for Strongyloides stercoralis infection

L2P2 – Clinical-epidemiological aspects of Strongyloides stercoralis infection.

L2P3 – Control of strongyloidiasis: a one-health approach.

L2P4 – Improving the diagnostic approach and pathophysiology knowledge in Strongyloides stercoralis infections

  1. NEGLECTED TROPICAL DISEASES (NTD)

Objectives: assessment of Neglected Tropical Diseases burden in not endemic countries; development of screening protocols/management of imported cases; enhancement of diagnostic approach and Neglected Tropical Diseases management in endemic and not endemic area. The biomedical research will be oriented to the study of new physiopathology aspects, new diagnostic and prognostic markers of different Neglected Tropical Diseases through the most modern technologies of genomics and proteomics.

Ongoing macro-projects:

L3P1 – Neglected infections, vulnerable populations

L3P2 – Unravelling the pathophysiology bases and developing of new diagnostic approaches for neglected tropical diseases

L3P3 – RF 2016-02361931 “Emerging Blood Protozoa in the immunocompromised population: novel strategies for screening, diagnosis, monitoring and clinical management”

ONGOING STUDIES (update 10/30/2020)